LZTS2 and PTEN collaboratively regulate ß-catenin in prostatic tumorigenesis

The leucine zipper tumor suppressor 2 (LZTS2) was identified as a tumor susceptibility gene within the 10q24.3 chromosomal region, and is approximately 15Mb from the PTEN locus. This region containing the both loci is frequently deleted in a variety of human malignancies, including prostate cancer....

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Yu, Eun-Jeong, Hooker, Erika, Johnson, Daniel T., Kwak, Mi Kyung, Zou, Kang, Luong, Richard, He, Yongfeng, Sun, Zijie
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360334/
https://ncbi.nlm.nih.gov/pubmed/28323888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174357
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