IκB kinase β phosphorylates Dok1 serines in response to TNF, IL-1, or γ radiation
Dok1 is an abundant Ras-GTPase-activating protein-associated tyrosine kinase substrate that negatively regulates cell growth and promotes migration. We now find that IκB kinase β (IKKβ) associated with and phosphorylated Dok1 in human epithelial cells and B lymphocytes. IKKβ phosphorylation of Dok1...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC536032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15574499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408061101 |
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