Diacerein inhibits the pro-atherogenic & pro-inflammatory effects of IL-1 on human keratinocytes & endothelial cells

We investigated IL-1-induced regulation of genes related to inflammation and atherogenesis in human keratinocytes and endothelial cells, and if ‘diacerein’, an oral IL-1 inhibiting drug currently approved for use in osteoarthritis, would reverse IL-1’s effects on these cells. Primary human keratinoc...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Mohan, Girish C., Zhang, Huayi, Bao, Lei, Many, Benjamin, Chan, Lawrence S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360272/
https://ncbi.nlm.nih.gov/pubmed/28323859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173981
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