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PIM1-minicircle as a therapeutic treatment for myocardial infarction

PIM1, a pro-survival gene encoding a serine/ threonine kinase, influences cell proliferation and survival. Modification of cardiac progenitor cells (CPCs) or cardiomyocytes with PIM1 using a lentivirus-based delivery method showed long-term improved cardiac function after myocardial infarction (MI)....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Liu, Nan, Wang, Bingyan J., Broughton, Kathleen M., Alvarez, Roberto, Siddiqi, Sailay, Loaiza, Rebeca, Nguyen, Nicky, Quijada, Pearl, Gude, Natalie, Sussman, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360264/
https://ncbi.nlm.nih.gov/pubmed/28323876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173963
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