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Combined tRNA modification defects impair protein homeostasis and synthesis of the yeast prion protein Rnq1
Modified nucleosides in tRNA anticodon loops such as 5-methoxy-carbonyl-methyl-2-thiouridine (mcm(5)s(2)U) and pseuduridine (Ψ) are thought to be required for an efficient decoding process. In Saccharomyces cerevisiae, the simultaneous presence of mcm(5)s(2)U and Ψ38 in tRNA(Gln)(UUG) was shown to m...
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| Gepubliceerd in: | Prion |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5360143/ https://ncbi.nlm.nih.gov/pubmed/28281930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2017.1284734 |
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