Safety and immunogenicity of GamEvac-Combi, a heterologous VSV- and Ad5-vectored Ebola vaccine: An open phase I/II trial in healthy adults in Russia

Ebola hemorrhagic fever, also known as Ebola virus disease or EVD, is one of the most dangerous viral diseases in humans and animals. In this open-label, dose-escalation clinical trial, we assessed the safety, side effects, and immunogenicity of a novel, heterologous prime-boost vaccine against Ebol...

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Publicado en:Hum Vaccin Immunother
Autores principales: Dolzhikova, I. V., Zubkova, O. V., Tukhvatulin, A. I., Dzharullaeva, A. S., Tukhvatulina, N. M., Shcheblyakov, D. V., Shmarov, M. M., Tokarskaya, E. A., Simakova, Y. V., Egorova, D. A., Scherbinin, D. N., Tutykhina, I. L., Lysenko, A. A., Kostarnoy, A. V., Gancheva, P. G., Ozharovskaya, T. A., Belugin, B. V., Kolobukhina, L. V., Pantyukhov, V. B., Syromyatnikova, S. I., Shatokhina, I. V., Sizikova, T. V., Rumyantseva, I. G., Andrus, A. F., Boyarskaya, N. V., Voytyuk, A. N., Babira, V. F., Volchikhina, S. V., Kutaev, D. A., Bel'skih, A. N., Zhdanov, K. V., Zakharenko, S. M., Borisevich, S. V., Logunov, D. Y., Naroditsky, B. S., Gintsburg, A. L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360131/
https://ncbi.nlm.nih.gov/pubmed/28152326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1238535
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