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Aurora A kinase amplifies a midzone phosphorylation gradient to promote high fidelity cytokinesis

Aurora B kinase (ABK) re-localizes from centromeres to the spindle midzone during cytokinesis where it is thought to provide a spatial cue for cytokinesis. While global ABK inhibition in Drosophila S2 cells results in macro- and multi-nucleated large cells, mis-localization of midzone ABK (mABK) by...

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Detalhes bibliográficos
Publicado no:Biol Bull
Main Authors: Ye, Anna A., Torabi, Julia, Maresca, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360107/
https://ncbi.nlm.nih.gov/pubmed/27638695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/689591
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