A Double-Blind, Randomized, Placebo-Controlled Clinical Trial of S-Adenosyl-(L)-Methionine (SAMe) Vs. Escitalopram in Major Depressive Disorder

OBJECTIVE: To examine the comparative antidepressant efficacy of S-adenosyl-(L)-methionine (SAMe) and escitalopram in a placebo-controlled, randomized, double-blind clinical trial. METHODS: 189 outpatients (49.7% female, mean age 45 ± 15 years) with DSM-IV-diagnosed major depressive disorder (MDD) w...

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Pubblicato in:J Clin Psychiatry
Autori principali: Mischoulon, David, Price, Lawrence H., Carpenter, Linda L., Tyrka, Audrey R., Papakostas, George I., Baer, Lee, Dording, Christina M., Clain, Alisabet J., Durham, Kelley, Walker, Rosemary, Ludington, Elizabeth, Fava, Maurizio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360105/
https://ncbi.nlm.nih.gov/pubmed/24500245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4088/JCP.13m08591
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