Decreased cortical FADD protein is associated with clinical dementia and cognitive decline in an elderly community sample

BACKGROUND: FADD (Fas-associated death domain) adaptor is a crucial protein involved in the induction of cell death but also mediates non-apoptotic actions via a phosphorylated form (p-Ser194-FADD). This study investigated the possible association of FADD forms with age-related neuropathologies, cog...

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Udgivet i:Mol Neurodegener
Main Authors: Ramos-Miguel, Alfredo, García-Sevilla, Jesús A., Barr, Alasdair M., Bayer, Thomas A., Falkai, Peter, Leurgans, Sue E., Schneider, Julie A., Bennett, David A., Honer, William G., García-Fuster, M. Julia
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360099/
https://ncbi.nlm.nih.gov/pubmed/28320441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0168-x
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