Dysregulated systemic lymphocytes affect the balance of osteogenic/adipogenic differentiation of bone mesenchymal stem cells after local irradiation

BACKGROUND: While it is known that irradiation can induce local and systemic bone loss over time, how focal irradiation induces systemic bone complications remains unclear. Immune cells are thought to be crucial to bone homeostasis, and abnormal immune cells lead to serious disruption of bone homeos...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Xu, Xiaoya, Li, Ruixia, Zhou, Yi, Zou, Qiong, Ding, Qiaoling, Wang, Jinfeng, Jin, Weifang, Hua, Guoqiang, Gao, Jianjun
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360074/
https://ncbi.nlm.nih.gov/pubmed/28320453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0527-0
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