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Ipilimumab-induced thrombotic thrombocytopenic purpura (TTP)

BACKGROUND: CTLA-4 (Cytotoxic T-lymphocyte-associated protein 4) was the first immune checkpoint receptor clinically targeted for use in cancer treatment. It is expressed exclusively on T-cells where its primary role is to regulate the amplitude of the early stages of T-cell activation.1 Ipilimumab,...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: King, Jeanelle, de la Cruz, Javier, Lutzky, Jose
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360069/
https://ncbi.nlm.nih.gov/pubmed/28344807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0224-7
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