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Ipilimumab-induced thrombotic thrombocytopenic purpura (TTP)
BACKGROUND: CTLA-4 (Cytotoxic T-lymphocyte-associated protein 4) was the first immune checkpoint receptor clinically targeted for use in cancer treatment. It is expressed exclusively on T-cells where its primary role is to regulate the amplitude of the early stages of T-cell activation.1 Ipilimumab,...
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| Publicado en: | J Immunother Cancer |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5360069/ https://ncbi.nlm.nih.gov/pubmed/28344807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0224-7 |
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