Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure

BACKGROUND: Mesenchymal stem cells (MSCs) have been studied for the treatment of acute liver failure (ALF) for several years. MSCs may exert their effect via complex paracrine mechanisms. Heme oxygenase (HO) 1, a rate-limiting enzyme in heme metabolism, exerts a wide range of anti-inflammatory, anti...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Zhang, Zhi-heng, Zhu, Wei, Ren, Hao-zhen, Zhao, Xin, Wang, Shuai, Ma, Hu-cheng, Shi, Xiao-lei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359839/
https://ncbi.nlm.nih.gov/pubmed/28320485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0524-3
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