False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum isolates lacking hrp2 and declining malaria transmission

BACKGROUND: Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used to determine whether persons with fever should be treated with anti-malarials. However, Plasmodium falciparum parasites with a deletion of the hrp2 gene yield false-negative RDTs and there are concerns the s...

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Dettagli Bibliografici
Pubblicato in:Malar J
Autori principali: Kozycki, Christina T., Umulisa, Noella, Rulisa, Stephen, Mwikarago, Emil I., Musabyimana, Jean Pierre, Habimana, Jean Pierre, Karema, Corine, Krogstad, Donald J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359811/
https://ncbi.nlm.nih.gov/pubmed/28320390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1768-1
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