Activation of KCNQ Channels Suppresses Spontaneous Activity in Dorsal Root Ganglion Neurons and Reduces Chronic Pain after Spinal Cord Injury

A majority of people who have sustained spinal cord injury (SCI) experience chronic pain after injury, and this pain is highly resistant to available treatments. Contusive SCI in rats at T10 results in hyperexcitability of primary sensory neurons, which contributes to chronic pain. KCNQ channels are...

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Publicado en:J Neurotrauma
Main Authors: Wu, Zizhen, Li, Lin, Xie, Fuhua, Du, Junhui, Zuo, Yan, Frost, Jeffrey A., Carlton, Susan M., Walters, Edgar T., Yang, Qing
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2017
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359643/
https://ncbi.nlm.nih.gov/pubmed/28073317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2016.4789
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