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Activation of KCNQ Channels Suppresses Spontaneous Activity in Dorsal Root Ganglion Neurons and Reduces Chronic Pain after Spinal Cord Injury

A majority of people who have sustained spinal cord injury (SCI) experience chronic pain after injury, and this pain is highly resistant to available treatments. Contusive SCI in rats at T10 results in hyperexcitability of primary sensory neurons, which contributes to chronic pain. KCNQ channels are...

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Bibliografske podrobnosti
izdano v:J Neurotrauma
Main Authors: Wu, Zizhen, Li, Lin, Xie, Fuhua, Du, Junhui, Zuo, Yan, Frost, Jeffrey A., Carlton, Susan M., Walters, Edgar T., Yang, Qing
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359643/
https://ncbi.nlm.nih.gov/pubmed/28073317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2016.4789
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