Activation of KCNQ Channels Suppresses Spontaneous Activity in Dorsal Root Ganglion Neurons and Reduces Chronic Pain after Spinal Cord Injury

A majority of people who have sustained spinal cord injury (SCI) experience chronic pain after injury, and this pain is highly resistant to available treatments. Contusive SCI in rats at T10 results in hyperexcitability of primary sensory neurons, which contributes to chronic pain. KCNQ channels are...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurotrauma
Prif Awduron: Wu, Zizhen, Li, Lin, Xie, Fuhua, Du, Junhui, Zuo, Yan, Frost, Jeffrey A., Carlton, Susan M., Walters, Edgar T., Yang, Qing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2017
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359643/
https://ncbi.nlm.nih.gov/pubmed/28073317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2016.4789
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