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A Heterotopic Xenograft Model of Human Airways for Investigating Fibrosis in Asthma

Limited in vivo models exist to investigate the lung airway epithelial role in repair, regeneration, and pathology of chronic lung diseases. Herein, we introduce a novel animal model in asthma—a xenograft system integrating a differentiating human asthmatic airway epithelium with an actively remodel...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Hackett, Tillie-Louise, Ferrante, Sarah C., Hoptay, Claire E., Engelhardt, John F., Ingram, Jennifer L., Zhang, Yulong, Alcala, Sarah E., Shaheen, Furquan, Matz, Ethan, Pillai, Dinesh K., Freishtat, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359536/
https://ncbi.nlm.nih.gov/pubmed/27788019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0065MA
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