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Lesch-Nyhan syndrome: The saga of metabolic abnormalities and self-injurious behavior

Lesch-Nyhan syndrome (LNS) is an X-linked recessive disorder of purine metabolism caused by a mutation in Xq26.2-q26.3 (OMIM 308000.0004). The presence of the diagnostic triad, i.e. signs of self-injurious behavior (SIB) and results of pedigree analysis and novel molecular biology & genetic test...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Intractable Rare Dis Res
Main Authors: Tewari, Nitesh, Mathur, Vijay Prakash, Sardana, Divesh, Bansal, Kalpana
Format: Artigo
Jezik:Inglês
Izdano: International Research and Cooperation Association for Bio & Socio-Sciences Advancement 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359358/
https://ncbi.nlm.nih.gov/pubmed/28357186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5582/irdr.2016.01076
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