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Profiling of Kidney Injury Biomarkers in Patients Receiving Cisplatin: Time-Dependent Changes in the Absence of Clinical Nephrotoxicity

The success of cisplatin-containing regimens to treat solid tumors is limited, in part, by nephrotoxicity. In rodents, several urinary proteins have emerged as more sensitive indicators of cisplatin-induced kidney injury. We sought to characterize time-dependent changes in the urinary concentrations...

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Détails bibliographiques
Publié dans:Clin Pharmacol Ther
Auteurs principaux: George, Blessy, Wen, Xia, Mercke, Nickie, Gomez, Madeleine, O’Bryant, Cindy, Bowles, Daniel W., Hu, Yichun, Hogan, Susan L., Joy, Melanie S., Aleksunes, Lauren M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359028/
https://ncbi.nlm.nih.gov/pubmed/28002630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.606
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