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Fixed-dose combination orally disintegrating tablets to treat cardiovascular disease: formulation, in vitro characterization and physiologically based pharmacokinetic modeling to assess bioavailability

Cardiovascular disease (CVD) is the leading cause of death among men and women worldwide. In CVD, hypertension and dyslipidemia commonly coexist and are managed through coadministration of amlodipine and atorvastatin, respectively. The case for fixed-dose combination (FDC) oral dosage forms and oral...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Drug Des Devel Ther
Κύριοι συγγραφείς: Dennison, Thomas J, Smith, Julian C, Badhan, Raj K, Mohammed, Afzal R
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Dove Medical Press 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358997/
https://ncbi.nlm.nih.gov/pubmed/28352156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S126035
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