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Fixed-dose combination orally disintegrating tablets to treat cardiovascular disease: formulation, in vitro characterization and physiologically based pharmacokinetic modeling to assess bioavailability

Cardiovascular disease (CVD) is the leading cause of death among men and women worldwide. In CVD, hypertension and dyslipidemia commonly coexist and are managed through coadministration of amlodipine and atorvastatin, respectively. The case for fixed-dose combination (FDC) oral dosage forms and oral...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Des Devel Ther
Prif Awduron: Dennison, Thomas J, Smith, Julian C, Badhan, Raj K, Mohammed, Afzal R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358997/
https://ncbi.nlm.nih.gov/pubmed/28352156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S126035
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