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Preexposure of MCF-7 breast cancer cell line to dexamethasone alters the cytotoxic effect of paclitaxel but not 5-fluorouracil or epirubicin chemotherapy

PURPOSE: Glucocorticoids (GCs) are often administered prior to any chemotherapeutics to prevent the secondary effects of anticancer agents. Glucocorticoid receptors (GRs) are expressed in several types of cancer cells, particularly in several histological types of breast cancer. Activation of GRs is...

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Bibliografiske detaljer
Udgivet i:Breast Cancer (Dove Med Press)
Main Authors: Buxant, Frederic, Kindt, Nadège, Noël, Jean-Christophe, Laurent, Guy, Saussez, Sven
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358959/
https://ncbi.nlm.nih.gov/pubmed/28352202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S120005
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