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TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes

Tudor containing protein 6 (TDRD6) is a male germ line-specific protein essential for chromatoid body (ChB) structure, elongated spermatid development and male fertility. Here we show that in meiotic prophase I spermatocytes TDRD6 interacts with the key protein arginine methyl transferase PRMT5, whi...

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Vydáno v:PLoS Genet
Hlavní autoři: Akpınar, Müge, Lesche, Mathias, Fanourgakis, Grigorios, Fu, Jun, Anasstasiadis, Konstantinos, Dahl, Andreas, Jessberger, Rolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358835/
https://ncbi.nlm.nih.gov/pubmed/28263986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006660
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