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Complement C3 inhibitor Cp40 attenuates xenoreactions in pig hearts perfused with human blood
BACKGROUND: The complement system plays a crucial role in acute xenogeneic reactions after cardiac transplantation. We used an ex vivo perfusion model to investigate the effect of Cp40, a compstatin analog and potent inhibitor of complement at the level of C3. METHODS: 15 wild-type pig hearts were e...
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| Publicado no: | Xenotransplantation |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358808/ https://ncbi.nlm.nih.gov/pubmed/27677785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12262 |
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