Candidate gene analyses of 3-dimensional dentoalveolar phenotypes in subjects with malocclusion

INTRODUCTION: Genetic studies of malocclusion etiology have identified 4 deleterious mutations in genes, DUSP6, ARHGAP21, FGF23, and ADAMTS1 in familial Class III cases. Although these variants may have large impacts on Class III phenotypic expression, their low frequency (<1%) makes them unlikel...

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Bibliographic Details
Published in:Am J Orthod Dentofacial Orthop
Main Authors: Weaver, Cole A., Miller, Steven F., da Fontoura, Clarissa S. G., Wehby, George L., Amendt, Brad A., Holton, Nathan E., Allareddy, Veeratrishul, Southard, Thomas E., Moreno Uribe, Lina M.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358674/
https://ncbi.nlm.nih.gov/pubmed/28257739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajodo.2016.08.027
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