PP38. LIMITATION OF EXTERNAL LIPID SOURCES INDUCES DIFFERENTIAL PROLIFERATIVE AND MORPHOLOGICAL RESPONSES IN ADULT AND PAEDIATRIC GBM CELLS

INTRODUCTION: The tumour microenvironment of glioblastoma multiforme (GBM) demonstrates gradients in oxygen and nutrients due to an improperly formed tumour vasculature. Cancer cells obtain lipids for membrane biogenesis through anabolic cellular metabolism or internalisation of lipoproteins from th...

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Publicado no:Neuro Oncol
Main Authors: Wood, Mr James, Kim, Dr Dong-Hyun, Alqahtani, Mr Safar, Smith, Dr Stuart, Barrett, Prof David, Grundy, Prof Richard, Rahman, Dr Ruman
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358606/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now293.038
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