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PP14. NETWORK ANALYSIS REVEALS INSIGHTS INTO H3F3A BIOLOGY IN PEDIATRIC GLIOBLASTOMA
BACKGROUND: H3 histone, family 3A (H3F3A) encodes H3.3 histone protein monomers, which plays a central role in chromatin structure and gene regulation. Recent studies have reported highly recurrent mutations affecting the N-terminal tail of H3.3 and causing amino acid substitution of lysine 27 to me...
Shranjeno v:
| izdano v: | Neuro Oncol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358576/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now293.013 |
| Oznake: |
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