Discordance in investigator-reported and adjudicated sudden death in TIOSPIR

Accurate and consistent determination of cause of death is challenging in chronic obstructive pulmonary disease (COPD) patients. TIOSPIR (N=17 135) compared the safety and efficacy of tiotropium Respimat 5/2.5 µg with HandiHaler 18 µg in COPD patients. All-cause mortality was a primary end-point. A...

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Publicat a:ERJ Open Res
Autors principals: Wise, Robert A., Kowey, Peter R., Austen, George, Mueller, Achim, Metzdorf, Norbert, Fowler, Andy, McGarvey, Lorcan P.
Format: Artigo
Idioma:Inglês
Publicat: European Respiratory Society 2017
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358526/
https://ncbi.nlm.nih.gov/pubmed/28344980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00073-2016
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