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Physiologically activated mammary fibroblasts promote postpartum mammary cancer

Women diagnosed with breast cancer within 5 years of childbirth have poorer prognosis than nulliparous or pregnant women. Weaning-induced breast involution is implicated, as the collagen-rich, immunosuppressive microenvironment of the involuting mammary gland is tumor promotional in mice. To investi...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Guo, Qiuchen, Minnier, Jessica, Burchard, Julja, Chiotti, Kami, Spellman, Paul, Schedin, Pepper
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358521/
https://ncbi.nlm.nih.gov/pubmed/28352652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89206
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