CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy

OBJECTIVE: The role of inflammation in structural and symptomatic osteoarthritis (OA) remains unclear. One key mediator of inflammation is the chemokine CCL2, primarily responsible for attracting monocytes to sites of injury. We investigated the role of CCL2 and its receptor CCR2 in experimental OA....

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Bibliografiska uppgifter
I publikationen:Osteoarthritis Cartilage
Huvudupphovsmän: Miotla Zarebska, J., Chanalaris, A., Driscoll, C., Burleigh, A., Miller, R.E., Malfait, A.M., Stott, B., Vincent, T.L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: W.B. Saunders For The Osteoarthritis Research Society 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358501/
https://ncbi.nlm.nih.gov/pubmed/27746376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.10.008
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