Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia

Gram-negative pneumonia is a dangerous illness, and bacterial dissemination to the bloodstream during the infection is strongly associated with death. Antibiotic resistance among the causative pathogens has resulted in diminishing treatment options against this infection. Hepcidin is the master regu...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Michels, Kathryn R., Zhang, Zhimin, Bettina, Alexandra M., Cagnina, R. Elaine, Stefanova, Debora, Burdick, Marie D., Vaulont, Sophie, Nemeth, Elizabeta, Ganz, Tomas, Mehrad, Borna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358492/
https://ncbi.nlm.nih.gov/pubmed/28352667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92002
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