Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration

Introduction. Macrophages are key players in complex biological processes. In response to environmental signals, macrophages undergo polarization towards a proinflammatory (M1) or anti-inflammatory (M2) phenotype. Sphingosine 1-phosphate (S1P) is a bioactive lysophospholipid that acts via 5 G-protei...

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發表在:Biomed Res Int
Main Authors: Müller, Jan, von Bernstorff, Wolfram, Heidecke, Claus-Dieter, Schulze, Tobias
格式: Artigo
語言:Inglês
出版: Hindawi 2017
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358463/
https://ncbi.nlm.nih.gov/pubmed/28367448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7584621
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