Fractionation of heparin by chromatography on a tissue plasminogen activator-Sepharose column.
Heparin stimulates the activity of tissue plasminogen activator (t-PA) and binds to t-PA. To study this interaction, a complex between t-PA and N-acetylated heparin was formed and then linked to Sepharose. This procedure selectively links the t-PA to the column because the acetylated heparin has no...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1990
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53584/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2106684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.5.1865 |
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