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Cas9-mediated genome editing in the methanogenic archaeon Methanosarcina acetivorans
Although Cas9-mediated genome editing has proven to be a powerful genetic tool in eukaryotes, its application in Bacteria has been limited because of inefficient targeting or repair; and its application to Archaea has yet to be reported. Here we describe the development of a Cas9-mediated genome-edi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358397/ https://ncbi.nlm.nih.gov/pubmed/28265068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618596114 |
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