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A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells

One of the hallmarks of cancer is the ability of tumor cells to invade surrounding tissues and metastasize. During metastasis, cancer cells degrade the extracellular matrix, which acts as a physical barrier, by developing specialized actin-rich membrane protrusion structures called invadopodia. The...

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Bibliografski detalji
Izdano u:J Cell Sci
Glavni autori: Goicoechea, Silvia M., Zinn, Ashtyn, Awadia, Sahezeel S., Snyder, Kyle, Garcia-Mata, Rafael
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358339/
https://ncbi.nlm.nih.gov/pubmed/28202690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.195552
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