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Retinoblastoma protein controls growth, survival and neuronal migration in human cerebral organoids
The tumor suppressor retinoblastoma protein (RB) regulates S-phase cell cycle entry via E2F transcription factors. Knockout (KO) mice have shown that RB plays roles in cell migration, differentiation and apoptosis, in developing and adult brain. In addition, the RB family is required for self-renewa...
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| 出版年: | Development |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358115/ https://ncbi.nlm.nih.gov/pubmed/28087635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143636 |
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