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Establishment and Use of New MDCK II Cells Overexpressing Both UGT1A1 and MRP2 to Characterize Flavonoid Metabolism via the Glucuronidation Pathway

SCOPE: The purpose of this study is to characterize how overexpression of an efflux transporter and an UDP-glucuronosyltransferase (UGT) affects the cellular kinetics of glucuronidation processes. METHODS AND RESULTS: A new MDCK II cell line overexpressing both MRP2 and UGT1A1 (MDCKII-UGT1A1/MRP2 ce...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Nutr Food Res
Egile Nagusiak: Wang, Meifang, Yang, Guangyi, He, Yu, Xu, Beibei, Zeng, Min, Yin, Taijun, Gao, Song, Hu, Ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358013/
https://ncbi.nlm.nih.gov/pubmed/26833852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201500321
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