IL-21 Receptor Antagonist Inhibits Differentiation of B Cells toward Plasmablasts upon Alloantigen Stimulation

Interaction between T follicular helper (Tfh) cells and B cells is complex and involves various pathways, including the production of IL-21 by the Tfh cells. Secretion of IL-21 results in B cell differentiation toward immunoglobulin-producing plasmablasts. In patients after kidney transplantation, t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: de Leur, Kitty, Dor, Frank J. M. F., Dieterich, Marjolein, van der Laan, Luc J. W., Hendriks, Rudi W., Baan, Carla C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357809/
https://ncbi.nlm.nih.gov/pubmed/28373876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00306
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