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Relation of renal cortical gluconeogenesis, glutamate content, and production of ammonia

Glutamate is an inhibitor of phosphate dependent glutaminase (PDG), and renal cortical glutamate is decreased in metabolic acidosis. It has been postulated previously that the rise in renal production of ammonia from glutamine in metabolic acidosis is due primarily to activation of cortical PDG as a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Pagliara, Anthony S., Goodman, A. David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1970
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4319966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106416
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