A multinational study distinguishing Alzheimer's and healthy patients using cerebrospinal fluid tau/Aβ42 cutoff with concordance to amyloid positron emission tomography imaging

INTRODUCTION: Changes in cerebrospinal fluid (CSF) tau and amyloid β (Aβ)42 accompany development of Alzheimer's brain pathology. Robust tau and Aβ42 immunoassays were developed to establish a tau/Aβ42 cutoff distinguishing mild-to-moderate Alzheimer's disease (AD) subjects from healthy el...

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Bibliografiska uppgifter
I publikationen:Alzheimers Dement (Amst)
Huvudupphovsmän: Mo, Yi, Stromswold, Julie, Wilson, Kimberly, Holder, Daniel, Sur, Cyrille, Laterza, Omar, Savage, Mary J., Struyk, Arie, Scheltens, Philip, Teunissen, Charlotte E., Burke, James, Macaulay, S. Lance, Bråthen, Geir, Sando, Sigrid Botne, White, Linda R., Weiss, Christy, Cowes, Arturo, Bush, Michele M., DeSilva, Ganga, Darby, David G., Rainey-Smith, Stephanie R., Surls, Jackie, Sagini, Eileen, Tanen, Michael, Altman, Amy, Luthman, Johan, Egan, Michael F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2017
Ämnen:
CSF Biomarkers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357677/
https://ncbi.nlm.nih.gov/pubmed/28349119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2017.02.004
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