Risk algorithms that include pathology adjustment for HER2 amplification need to make further downward adjustments in likelihood scores

To assess the need for adjustment in the likelihood of germline BRCA1/2 mutations in women with HER2+ breast cancers. We analysed primary mutation screens on women with breast cancer with unequivocal HER2 overexpression and assessed the likelihood of BRCA1/BRCA2 mutations by age, oestrogen receptor...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Fam Cancer
Päätekijät: Evans, D. G., Woodward, E. R., Howell, S. J., Verhoef, S., Howell, A., Lalloo, F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Netherlands 2016
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357509/
https://ncbi.nlm.nih.gov/pubmed/27796713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-016-9942-0
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia