Activated ERK1/2 increases CD44 in glomerular parietal epithelial cells leading to matrix expansion

The glycoprotein CD44 is barely detected in normal mouse and human glomeruli, but is increased in glomerular parietal epithelial cells following podocyte injury in focal segmental glomerulosclerosis (FSGS). To determine the biological role and regulation of CD44 in these cells, we employed an in viv...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Roeder, Sebastian S., Barnes, Taylor J., Lee, Jonathan S., Kato, India, Eng, Diana G., Kaverina, Natalya V., Sunseri, Maria W., Daniel, Christoph, Amann, Kerstin, Pippin, Jeffrey W., Shankland, Stuart J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357449/
https://ncbi.nlm.nih.gov/pubmed/27998643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.10.015
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