H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis

Dynamic changes in histone modifications under various physiological cues play important roles in gene transcription and cancer. Identification of new histone marks critical for cancer development is of particular importance. Here we show that, in a glucose-dependent manner, E3 ubiquitin ligase NEDD...

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Publicat a:Nat Commun
Autors principals: Zhang, Xian, Li, Binkui, Rezaeian, Abdol Hossein, Xu, Xiaohong, Chou, Ping-Chieh, Jin, Guoxiang, Han, Fei, Pan, Bo-Syong, Wang, Chi-Yun, Long, Jie, Zhang, Anmei, Huang, Chih-Yang, Tsai, Fuu-Jen, Tsai, Chang-Hai, Logothetis, Christopher, Lin, Hui-Kuan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357315/
https://ncbi.nlm.nih.gov/pubmed/28300060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14799
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