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Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal

The transposition of bacteriophage Mu serves as a model system for understanding DDE transposases and integrases. All available structures of these enzymes at the end of the transposition reaction, including Mu, exhibit significant bends in the transposition target site DNA. Here we use Mu to invest...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fuller, James R, Rice, Phoebe A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357137/
https://ncbi.nlm.nih.gov/pubmed/28177285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21777
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