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Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal

The transposition of bacteriophage Mu serves as a model system for understanding DDE transposases and integrases. All available structures of these enzymes at the end of the transposition reaction, including Mu, exhibit significant bends in the transposition target site DNA. Here we use Mu to invest...

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Vydáno v:eLife
Hlavní autoři: Fuller, James R, Rice, Phoebe A
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357137/
https://ncbi.nlm.nih.gov/pubmed/28177285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21777
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