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Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal

The transposition of bacteriophage Mu serves as a model system for understanding DDE transposases and integrases. All available structures of these enzymes at the end of the transposition reaction, including Mu, exhibit significant bends in the transposition target site DNA. Here we use Mu to invest...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Fuller, James R, Rice, Phoebe A
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357137/
https://ncbi.nlm.nih.gov/pubmed/28177285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21777
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