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Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells
We developed an allele-specific assay for transposase-accessible chromatin with high-throughput sequencing (ATAC–seq) to genotype and profile active regulatory DNA across the genome. Using a mouse hybrid F(1) system, we found that monoallelic DNA accessibility across autosomes was pervasive, develop...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357084/ https://ncbi.nlm.nih.gov/pubmed/28112738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3769 |
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