Surface-modified gatifloxacin nanoparticles with potential for treating central nervous system tuberculosis

A new nanocarrier is developed for the passage of gatifloxacin through the blood–brain barrier to treat central nervous system tuberculosis. Gatifloxacin nanoparticles were prepared by nanoprecipitation using poly(lactic-co-glycolic acid) (PLGA) 502 and polysorbate 80 or Labrafil as surface modifier...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Marcianes, Patricia, Negro, Sofia, García-García, Luis, Montejo, Consuelo, Barcia, Emilia, Fernández-Carballido, Ana
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357078/
https://ncbi.nlm.nih.gov/pubmed/28331318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S130908
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