Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients

Familial adenomatous polyposis (FAP) is an autosomal-dominantly inherited form of colorectal cancer (CRC) caused by mutation in the adenomatous polyposis coli (APC) gene. Our ability to exhaustively screen for APC mutations identify microsatellite-stable and APC-mutation negative familial CRC patien...

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Bibliographic Details
Published in:PLoS One
Main Authors: Thean, Lai Fun, Wong, Yu Hui, Lo, Michelle, Loi, Carol, Chew, Min Hoe, Tang, Choong Leong, Cheah, Peh Yean
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357012/
https://ncbi.nlm.nih.gov/pubmed/28306719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173772
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