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Novel amphiphilic folic acid-cholesterol-chitosan micelles for paclitaxel delivery

In order to decrease the toxicity of paclitaxel (PTX) and increase the efficiency, we developed an amphiphilic PTX injection system using a biodegradable and biocompatible polymer synthesized by folic acid, cholesterol, and chitosan (FACC). This FACC-based polymer had a low critical concentration (6...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cheng, Li-Chun, Jiang, Yan, Xie, Yu, Qiu, Lu-Lu, Yang, Qing, Lu, Hui-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356884/
https://ncbi.nlm.nih.gov/pubmed/27926514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13757
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