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A multi-step classifier addressing cohort heterogeneity improves performance of prognostic biomarkers in three cancer types

Cancer research continues to highlight the extensive genetic diversity that exists both between and within tumors. This intrinsic heterogeneity poses one of the central challenges to predicting patient clinical outcome and the personalization of treatments. Despite progress in some individual tumor...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Patrick, Ellis, Schramm, Sarah-Jane, Ormerod, John T, Scolyer, Richard A, Mann, Graham J, Mueller, Samuel, Yang, Jean Y.H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356843/
https://ncbi.nlm.nih.gov/pubmed/27833072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13203
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