Droplet digital PCR is a powerful technique to demonstrate frequent FGFR1 duplication in dysembryoplastic neuroepithelial tumors

Dysembryoplastic neuroepithelial tumors (DNT) share V600E mutation in the BRAF gene with other low grade neuroepithelial tumors (LGNTs). FGFR1 internal tandem duplication of the tyrosine-kinase domain (FGFR1-ITD), another genetic alteration that also leads to MAP kinase pathway alteration, has been...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Fina, Frédéric, Barets, Doriane, Colin, Carole, Bouvier, Corinne, Padovani, Laëtitia, Nanni-Metellus, Isabelle, Ouafik, L’Houcine, Scavarda, Didier, Korshunov, Andrey, Jones, David T.W., Figarella-Branger, Dominique
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356784/
https://ncbi.nlm.nih.gov/pubmed/27791984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12881
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