The transfer of multigene panel testing for hereditary breast and ovarian cancer to healthcare: What are the implications for the management of patients and families?

Until recently, the molecular diagnosis of hereditary breast and ovarian cancer (HBOC) was mostly based on BRCA1/2 testing. Next generation sequencing and the recent discovery of new genes involved in HBOC now permit the transfer of genomic capture targeting multiple candidate genes from research to...

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Publicado en:Oncotarget
Autores principales: Eliade, Marie, Skrzypski, Jeremy, Baurand, Amandine, Jacquot, Caroline, Bertolone, Geoffrey, Loustalot, Catherine, Coutant, Charles, Guy, France, Fumoleau, Pierre, Duffourd, Yannis, Arnould, Laurent, Delignette, Alexandra, Padéano, Marie-Martine, Lepage, Côme, Raichon-Patru, Géraldine, Boudrant, Axelle, Bône-Lépinoy, Marie-Christine, Villing, Anne-Laure, Charpin, Aurélie, Peignaux, Karine, Chevrier, Sandy, Vegran, Frédérique, Ghiringhelli, François, Boidot, Romain, Sevenet, Nicolas, Lizard, Sarab, Faivre, Laurence
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
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Priority Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356770/
https://ncbi.nlm.nih.gov/pubmed/27779110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12699
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