YWHAE silencing induces cell proliferation, invasion and migration through the up-regulation of CDC25B and MYC in gastric cancer cells: new insights about YWHAE role in the tumor development and metastasis process

We previously observed reduced YWHAE (14-3-3ε) protein expression in a small set of gastric cancer samples. YWHAE may act as a negative regulator of the cyclin CDC25B, which is a transcriptional target of MYC oncogene. The understanding of YWHAE role and its targets is important for the better knowl...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Leal, Mariana Ferreira, Ribeiro, Helem Ferreira, Rey, Juan Antonio, Pinto, Giovanny Rebouças, Smith, Marília Cardoso, Moreira-Nunes, Caroline Aquino, Assumpção, Paulo Pimentel, Lamarão, Leticia Martins, Calcagno, Danielle Queiroz, Montenegro, Raquel Carvalho, Burbano, Rommel Rodriguez
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356744/
https://ncbi.nlm.nih.gov/pubmed/27863420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13381
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