Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer

COX-2 expression level and prognostic value are still a matter of debate in breast cancer (BC). We addressed these points in the context of PIK3CA mutational status. Based on an interesting study of aspirin efficacy in colorectal cancer, we hypothesized that celecoxib antitumoral activity may be res...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tury, Sandrine, Becette, Véronique, Assayag, Franck, Vacher, Sophie, Benoist, Camille, Kamal, Maud, Marangoni, Elisabetta, Bièche, Ivan, Lerebours, Florence, Callens, Céline
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356723/
https://ncbi.nlm.nih.gov/pubmed/27835884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13200
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